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Daily Digest: Prioritizing potentially cancer-causing mutations in real-world cancer genomics, and more ...

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Prioritizing potentially cancer-causing mutations in real-world cancer genomics
Overview of a framework for prioritizing variants of uncertain significance (VUS) identified by comprehensive genomic profiling (CGP)
By Hiroshima University
Hiroshima University researchers have developed a practical framework to identify candidate pathogenic variants hidden among the large number of variants of uncertain significance (VUS) detected in comprehensive genomic profiling (CGP) of cancers.



Investigating the relationship of diet and heart disease burden
By Springer Nature
A poor diet remains a leading contributor to ischaemic heart disease, according to an analysis from 204 countries over a 30-year period



Lingnan University scholars co-develop novel interfacial structure that achieves highly efficient and stable tandem solar cells - findings published in leading international journal Nature Communications
Conventional strategies often lead to the uncontrolled diffusion of ligand molecules into the perovskite bulk or their severe loss during solvent washing, failing to form an effective ligand layer. The research team proposes a novel strategy that successfully immobilises the ligand molecules onto the SAM molecules, constructing a localised 2D/3D structure.
By Lingnan University
In response to the global demand for clean energy transition, tandem solar cells are recognised as a crucial next-generation technology that will significantly improve solar power efficiency.



A "breathing" lung organoid enables measurement of lung stiffness
By Institute of Industrial Science, The University of Tokyo (UTokyo-IIS)
Researchers develop a system that inflates human lung organoids from within to analyze lung mechanics



A smarter approach to testing reproductive safety
By Hokkaido University
A new platform could improve reproductive toxicity testing by enhancing both efficiency and ethical standards



Veterinarians in Japan and the UK view animal welfare through different cultural lenses
By Hokkaido University
A new international survey reveals clear differences in how veterinarians and animal welfare scientists in Japan and the UK perceive animal welfare, particularly animal behaviour.



Decline in Japanese chum salmon linked to climate change
By Hokkaido University
Loss of habitat along their migratory routes may be driving the recent decline in Japanese chum salmon populations



A fluorescent dye that works in superacidic environments
By Hokkaido University
Opening new possibilities for fluorescence-based imaging in extreme environments, from bioimaging to advanced materials



Into the fungal unknown: New tool maps fungal gene functions without reference genomes
Overview of the fungal transcriptome functional annotation workflow and downstream functional analysis
By Hiroshima University
Researchers at Hiroshima University have developed a new tool to quickly and accurately map fungal gene functions, even for species that have never been studied before.


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